陆献瑜，Professor of Pathologyat Sun Yat-sen University Cancer Cen-ter, was born in December 1928. Shehas been engaged in clinical diagnosis;teaching and research work for severaldecades, and made a great achievement.
Prof. Lu worked precisely and accumulated abundantexperience on diagnosis of difficult cases. She differentiatedmany specious cancer cases and rectified many wrong diag-noses to avoid unnecessary radiotherapy, chemo-therapy andradical operations. Also she compiled textbooks and heldmany training lessons of tumors. A lot of professionals spe-cializing in pathology have been trained. Prof. Lu devotedherself to the research of nasopharynx, liver, breast, thyroidcarcinomas and malignant lymphoma. Remarkable successeshave been achieved. 58 research papers were published. Shecompiled the electrical teaching material of clinical patholo-gy which was entitled "Nasopharyngeal Carcinomas, Nasaland other Nasopharyngeal Diseases" and won the 2nd prizeof audio-visual aid textbook of higher education.
Section 1 General outline
1.The pathologic category of nasopharyngeal carcinoma (NPc)
2.Problems concerning pathohistological classification of NPC
3.Clinical symptoms and diagnosis of NPC
4.Differential diagnosis of nasopharyngeal carcinoma (NPC),other benign and malignant tumors of nose, nasopharynx and
tumor-like inflammatory diseases
5.Some problems concerning mis-diagnosis of NPC
6.Some probloms concerning treatment of NPC
Section 2 Pathology atlas
1. Gross findings of nasopharyngeal carcinoma (NPC)
and other nasopharyngeal diseases: sketch
3.Histopathological features of NPC and other diseases of nasopharynx
4.Benign and malignant tumors originated from mes-enchymal tissue in nasopharynx
5.Tumors and other diseases of nose
Sun Yat-sen University Cancer Center is a well known in-stitution for diagnosis, treatment and research work on na-sopharyngeal carcinomas （NPC）. The affiliated hospital hasadmitted and treated thousands of patients coming from all overthe country and the southeastern Asia. In order to providingmore facilities and references in contributing to training ofmedical professionals and to raise further the diagnosis and re-search level of NPC, the authors compiled this atlas by collect-ing photographs with either gross or microscopic findings from211 248 biopsies and 8,848 autopsies. Among them, a few cas-es are from Sun Yat-sen College of Medical Sciences. We hopeit will enrich further the documents of pathology, oncology andotorhino laryngology.
Prof. Liang Bo-qiang is one of the founders of pathologyin China. He had initiated the work on study/diagnosis/treat-ment of NPC in China. He had made great pioneer achieve-ments in the field of histopathological classification, biologicalbehavior, origin of NPC and put forward the Liang's classifica-tion of NPC, which is significant for further investigation of NPC.
NPC could invade orbit through many routes: it can enterthe orbit through inferior and superior orbital fissure; come in-to pterygopalatine fossa along pterygoid canal; enter inner orbitthough orbital apex. Posterior ethmoidal cells are involvedthrough posterior naris, thus entering the orbit. If areas aroundauditory tube are involved frequently, thus invading petrosphe-noidal space along fasciae and II1, IV and V pairs of cranialnerves, the patients may have paralysis of eye movement.What's more, if trigeminal nerve or optic nerve is involved, thepatients may have sensory disturbance of nasociliary nerve,eyeball, face, nasal cavity mucosa, lacrimal gland and uppereyelid. Finally, the patients may become blind in one or botheyes. If cervical sympathetic ganglia is involved, the patientmay have Homer's Sign, which includes myosis, blepharophi-mosis and endoophthalmos. If NPC enters the orbit by way ofextracranial passageway, the patients may have exophthalmiafirst, may be with or without cranial nerves symptoms.